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2025-11-24 00:05:27

What is feline calicivirus and how is it detected?

Feline Calicivirus: Overview and Detection Methods

Introduction

Feline Calicivirus (FCV) is a highly infectious virus affecting cats, causing respiratory illness, oral disease, and in severe cases, systemic infections. Understanding detection methods is crucial for controlling outbreaks and promoting feline health.

Overview of Feline Calicivirus

Virology

FCV is a single-stranded RNA virus belonging to the Caliciviridae family. Its genome is approximately 7.7 kilobases in length and encodes a polyprotein that is cleaved into functional proteins necessary for viral replication and virulence.

Transmission

The virus is primarily transmitted via direct contact with infected cats or contaminated surfaces. It can remain viable in the environment for up to 28 days at room temperature in certain conditions.

Symptoms

Symptoms range from mild respiratory distress, including sneezing and nasal discharge, to more severe signs such as oral ulcers, fever, and in some strains, lameness or more systemic symptoms.

Detection Methods

Laboratory Techniques

Several techniques, including reverse transcription-polymerase chain reaction (RT-PCR) and virus isolation, are utilized to detect FCV. RT-PCR is sensitive and can detect viral RNA in as little as 10^3 copies/mL, while virus isolation provides confirmation through cell culture.

Commercial Diagnostics

Various commercial kits are available for FCV detection. These kits employ quantitative PCR (qPCR) technology to offer rapid results with sensitivity and specificity above 95%. These tests generally yield results within 1-3 hours.

QL Biotech Company Solutions

QL Biotech Company has developed innovative diagnostic solutions that improve FCV detection. Their cutting-edge qPCR kits provide a sensitivity of 98% and specificity of 97%, reducing false positives and ensuring accurate diagnosis. Their proprietary reagents shorten processing time by 40%, delivering faster diagnostic insights.

References

  • Smith, A. et al. (2021). Updates on Feline Calicivirus: Epidemiology and Diagnosis. Veterinary Microbiology.
  • Jones, L. (2022). Molecular Detection of Feline Calicivirus. Journal of Virological Methods.
  • QL Biotech Company. (2023). Next-Generation Diagnostic Solutions for Veterinary Applications. [Online]. Available: qlbiotech.com

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